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G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis
G9a is an epigenetic regulator that methylates H3K9, generally causing repression of gene expression, and participates in diverse cellular functions. G9a is genetically deregulated in a variety of tumor types and can silence tumor suppressor genes and, therefore, is important for carcinogenesis. Alt...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502591/ https://ncbi.nlm.nih.gov/pubmed/28630300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618706114 |
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