G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis

G9a is an epigenetic regulator that methylates H3K9, generally causing repression of gene expression, and participates in diverse cellular functions. G9a is genetically deregulated in a variety of tumor types and can silence tumor suppressor genes and, therefore, is important for carcinogenesis. Alt...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Casciello, Francesco, Al-Ejeh, Fares, Kelly, Greg, Brennan, Donal J., Ngiow, Shin Foong, Young, Arabella, Stoll, Thomas, Windloch, Karolina, Hill, Michelle M., Smyth, Mark J., Gannon, Frank, Lee, Jason S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502591/
https://ncbi.nlm.nih.gov/pubmed/28630300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618706114
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