Clinical features of acquired resistance to anti–PD-1 therapy in advanced melanoma

Anti–PD-1 therapy has improved clinical outcomes in advanced melanoma, but most patients experience intrinsic resistance. Responding patients can develop acquired resistance to anti–PD-1. We retrospectively reviewed 488 patients treated with anti–PD-1 from three academic centers and identified 36 pa...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Wang, Daniel Y., Eroglu, Zeynep, Ozgun, Alpaslan, Leger, Paul D., Zhao, Shilin, Ye, Fei, Luke, Jason J., Joseph, Richard W., Haq, Rizwan, Ott, Patrick A., Hodi, F. Stephen, Sosman, Jeffrey A., Johnson, Douglas B., Buchbinder, Elizabeth I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502536/
https://ncbi.nlm.nih.gov/pubmed/28396509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0287
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