Clinical features of acquired resistance to anti–PD-1 therapy in advanced melanoma

Anti–PD-1 therapy has improved clinical outcomes in advanced melanoma, but most patients experience intrinsic resistance. Responding patients can develop acquired resistance to anti–PD-1. We retrospectively reviewed 488 patients treated with anti–PD-1 from three academic centers and identified 36 pa...

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Publié dans:Cancer Immunol Res
Auteurs principaux: Wang, Daniel Y., Eroglu, Zeynep, Ozgun, Alpaslan, Leger, Paul D., Zhao, Shilin, Ye, Fei, Luke, Jason J., Joseph, Richard W., Haq, Rizwan, Ott, Patrick A., Hodi, F. Stephen, Sosman, Jeffrey A., Johnson, Douglas B., Buchbinder, Elizabeth I.
Format: Artigo
Langue:Inglês
Publié: 2017
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502536/
https://ncbi.nlm.nih.gov/pubmed/28396509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0287
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