Enhancing dengue virus maturation using a stable furin over-expressing cell line

Flaviviruses are positive-stranded RNA viruses that incorporate envelope (E) and premembrane (prM) proteins into the virion. Furin-mediated cleavage of prM defines a required maturation step in the flavivirus lifecycle. Inefficient prM cleavage results in structurally heterogeneous virions with uniq...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Virology
Huvudupphovsmän: Mukherjee, Swati, Sirohi, Devika, Dowd, Kimberly A., Chen, Zhenguo, Diamond, Michael S., Kuhn, Richard J., Pierson, Theodore C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502530/
https://ncbi.nlm.nih.gov/pubmed/27420797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2016.06.022
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk