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Base-Pair Resolution Genome-Wide Mapping Of Active RNA polymerases using Precision Nuclear Run-On (PRO-seq)
We provide a protocol for precision nuclear run-on sequencing (PRO-seq) and its variant, PRO-cap, which map the location of active RNA polymerases (PRO-seq) or transcription start sites (TSSs) (PRO-cap) genome-wide at high resolution. The density of RNA polymerases at a particular genomic locus dire...
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Pubblicato in: | Nat Protoc |
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Autori principali: | , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502525/ https://ncbi.nlm.nih.gov/pubmed/27442863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2016.086 |
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