Essential role of CCL21 in establishment of central self-tolerance in T cells

The chemokine receptor CCR7 directs T cell relocation into and within lymphoid organs, including the migration of developing thymocytes into the thymic medulla. However, how three functional CCR7 ligands in mouse, CCL19, CCL21Ser, and CCL21Leu, divide their roles in immune organs is unclear. By prod...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Kozai, Mina, Kubo, Yuki, Katakai, Tomoya, Kondo, Hiroyuki, Kiyonari, Hiroshi, Schaeuble, Karin, Luther, Sanjiv A., Ishimaru, Naozumi, Ohigashi, Izumi, Takahama, Yousuke
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502431/
https://ncbi.nlm.nih.gov/pubmed/28611158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161864
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