Downregulation of Smac attenuates H(2)O(2)-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells

BACKGROUND: Second mitochondria-derived activator of caspases (Smac) is reported to promote apoptosis. Given the important role of apoptosis in cataract development, the aim of this study was to investigate whether Smac induces human lens epithelial cell (HLEC) apoptosis via endoplasmic reticulum st...

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Bibliografische gegevens
Gepubliceerd in:Medicine (Baltimore)
Hoofdauteurs: De-qian, Kong, Yue, Liu, Li, Li, Guangying, Zheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wolters Kluwer Health 2017
Onderwerpen:
5800
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502174/
https://ncbi.nlm.nih.gov/pubmed/28682901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000007419
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