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Downregulation of Smac attenuates H(2)O(2)-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells

BACKGROUND: Second mitochondria-derived activator of caspases (Smac) is reported to promote apoptosis. Given the important role of apoptosis in cataract development, the aim of this study was to investigate whether Smac induces human lens epithelial cell (HLEC) apoptosis via endoplasmic reticulum st...

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Detalhes bibliográficos
Publicado no:Medicine (Baltimore)
Main Authors: De-qian, Kong, Yue, Liu, Li, Li, Guangying, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Health 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502174/
https://ncbi.nlm.nih.gov/pubmed/28682901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000007419
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