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Downregulation of Smac attenuates H(2)O(2)-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells

BACKGROUND: Second mitochondria-derived activator of caspases (Smac) is reported to promote apoptosis. Given the important role of apoptosis in cataract development, the aim of this study was to investigate whether Smac induces human lens epithelial cell (HLEC) apoptosis via endoplasmic reticulum st...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Medicine (Baltimore)
Prif Awduron: De-qian, Kong, Yue, Liu, Li, Li, Guangying, Zheng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wolters Kluwer Health 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502174/
https://ncbi.nlm.nih.gov/pubmed/28682901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000007419
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