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Downregulation of Smac attenuates H(2)O(2)-induced apoptosis via endoplasmic reticulum stress in human lens epithelial cells

BACKGROUND: Second mitochondria-derived activator of caspases (Smac) is reported to promote apoptosis. Given the important role of apoptosis in cataract development, the aim of this study was to investigate whether Smac induces human lens epithelial cell (HLEC) apoptosis via endoplasmic reticulum st...

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Publicat a:Medicine (Baltimore)
Autors principals: De-qian, Kong, Yue, Liu, Li, Li, Guangying, Zheng
Format: Artigo
Idioma:Inglês
Publicat: Wolters Kluwer Health 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502174/
https://ncbi.nlm.nih.gov/pubmed/28682901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000007419
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