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A Fast Association Test for Identifying Pathogenic Variants Involved in Rare Diseases
We present a rapid and powerful inference procedure for identifying loci associated with rare hereditary disorders using Bayesian model comparison. Under a baseline model, disease risk is fixed across all individuals in a study. Under an association model, disease risk depends on a latent bipartitio...
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| Publicado no: | Am J Hum Genet |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501869/ https://ncbi.nlm.nih.gov/pubmed/28669401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.05.015 |
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