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Quantifying the Impact of Non-coding Variants on Transcription Factor-DNA Binding

Many recent studies have emphasized the importance of genetic variants and mutations in cancer and other complex human diseases. The overwhelming majority of these variants occur in non-coding portions of the genome, where they can have a functional impact by disrupting regulatory interactions betwe...

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Detalhes bibliográficos
Publicado no:Res Comput Mol Biol
Main Authors: Zhao, Jingkang, Li, Dongshunyi, Seo, Jungkyun, Allen, Andrew S., Gordân, Raluca
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501730/
https://ncbi.nlm.nih.gov/pubmed/28691125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-56970-3_21
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