GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR

Glutathione reductase (GSR), a key member of the glutathione antioxidant defense system, converts oxidized glutathione (GSSG) to reduced glutathione (GSH) and maintains the intracellular glutathione redox state to protect the cells from oxidative damage. Previous reports have shown that Gsr deficien...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Han, Chul, Kim, Mi-Jung, Ding, Dalian, Park, Hyo-Jin, White, Karessa, Walker, Logan, Gu, Tongjun, Tanokura, Masaru, Yamasoba, Tatsuya, Linser, Paul, Salvi, Richard, Someya, Shinichi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501606/
https://ncbi.nlm.nih.gov/pubmed/28686716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180817
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