GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR

Glutathione reductase (GSR), a key member of the glutathione antioxidant defense system, converts oxidized glutathione (GSSG) to reduced glutathione (GSH) and maintains the intracellular glutathione redox state to protect the cells from oxidative damage. Previous reports have shown that Gsr deficien...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Han, Chul, Kim, Mi-Jung, Ding, Dalian, Park, Hyo-Jin, White, Karessa, Walker, Logan, Gu, Tongjun, Tanokura, Masaru, Yamasoba, Tatsuya, Linser, Paul, Salvi, Richard, Someya, Shinichi
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2017
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501606/
https://ncbi.nlm.nih.gov/pubmed/28686716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180817
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