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Metabolic labeling in middle-down proteomics allows for investigation of the dynamics of the histone code
BACKGROUND: Middle-down mass spectrometry (MS), i.e., analysis of long (~50–60 aa) polypeptides, has become the method with the highest throughput and accuracy for the characterization of combinatorial histone posttranslational modifications (PTMs). The discovery of histone readers with multiple dom...
Shranjeno v:
| izdano v: | Epigenetics Chromatin |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501349/ https://ncbi.nlm.nih.gov/pubmed/28683815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-017-0139-z |
| Oznake: |
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