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HAMS: High-Affinity Mass Spectrometry Screening. A high-throughput screening method for identifying the tightest-binding lead compounds for target proteins with no false positive identifications
A major challenge in drug discovery is the identification of high affinity lead compounds that bind a particular target protein; these leads are typically identified by high throughput screens. Mass spectrometry has become a detection method of choice in drug screening assays because the target and...
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| Publicado no: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501305/ https://ncbi.nlm.nih.gov/pubmed/27600575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1472-3 |
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