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HiChIP: Efficient and sensitive analysis of protein-directed genome architecture

Genome conformation is central to gene control but challenging to interrogate. Here we present HiChIP, a protein-centric chromatin conformation method. HiChIP improves the yield of conformation-informative reads by over 10-fold and lowers input requirement over 100-fold relative to ChIA-PET. HiChIP...

詳細記述

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書誌詳細
出版年:Nat Methods
主要な著者: Mumbach, Maxwell R., Rubin, Adam J., Flynn, Ryan A., Dai, Chao, Khavari, Paul A., Greenleaf, William J., Chang, Howard Y.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501173/
https://ncbi.nlm.nih.gov/pubmed/27643841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3999
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