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HiChIP: Efficient and sensitive analysis of protein-directed genome architecture
Genome conformation is central to gene control but challenging to interrogate. Here we present HiChIP, a protein-centric chromatin conformation method. HiChIP improves the yield of conformation-informative reads by over 10-fold and lowers input requirement over 100-fold relative to ChIA-PET. HiChIP...
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| Veröffentlicht in: | Nat Methods |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501173/ https://ncbi.nlm.nih.gov/pubmed/27643841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3999 |
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