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Docetaxel Accumulates in Lymphatic Circulation Following Subcutaneous Delivery as Compared to Intravenous Delivery in Rats

BACKGROUND: The circulatory pathway for particles deposited outside of blood capillaries has not been well characterized for non-traditionally-delivered chemotherapeutics. MATERIALS AND METHODS: Blood and lymph pharmacokinetics of docetaxel (5 mg/kg) and carboplatin (14 and 28 mg/kg) following subcu...

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Detalhes bibliográficos
Publicado no:Anticancer Res
Main Authors: WORLEY, DEANNA R., HANSEN, RYAN J., WITTENBURG, LUKE A., CHUBB, LAURA S., GUSTAFSON, DANIEL L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501171/
https://ncbi.nlm.nih.gov/pubmed/27798866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/anticanres.11076
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