Cyclophosphamide Facilitates Antitumor Efficacy against Subcutaneous Tumors following Intravenous Delivery of Reovirus

PURPOSE: The purpose of the present study was to investigate whether it is possible to achieve truly systemic delivery of oncolytic reovirus, in immunocompetent hosts, using cyclophosphamide to overcome some of the barriers to effective intratumoral delivery and replication of i.v. injected virus. E...

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Detalhes bibliográficos
Main Authors: Qiao, Jian, Wang, Hongxun, Kottke, Timothy, White, Christine, Twigger, Katie, Diaz, Rosa Maria, Thompson, Jill, Selby, Peter, de Bono, Johann, Melcher, Alan, Pandha, Hardev, Coffey, Matt, Vile, Richard, Harrington, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046731/
https://ncbi.nlm.nih.gov/pubmed/18172278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1510
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