Cyclophosphamide Facilitates Antitumor Efficacy against Subcutaneous Tumors following Intravenous Delivery of Reovirus

PURPOSE: The purpose of the present study was to investigate whether it is possible to achieve truly systemic delivery of oncolytic reovirus, in immunocompetent hosts, using cyclophosphamide to overcome some of the barriers to effective intratumoral delivery and replication of i.v. injected virus. E...

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Autores principales: Qiao, Jian, Wang, Hongxun, Kottke, Timothy, White, Christine, Twigger, Katie, Diaz, Rosa Maria, Thompson, Jill, Selby, Peter, de Bono, Johann, Melcher, Alan, Pandha, Hardev, Coffey, Matt, Vile, Richard, Harrington, Kevin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046731/
https://ncbi.nlm.nih.gov/pubmed/18172278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1510
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