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GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes

Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, ther...

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Bibliografiska uppgifter
I publikationen:F1000Res
Huvudupphovsmän: van den Broek, Evert, van Lieshout, Stef, Rausch, Christian, Ylstra, Bauke, van de Wiel, Mark A., Meijer, Gerrit A., Fijneman, Remond J.A., Abeln, Sanne
Materialtyp: Artigo
Språk:Inglês
Publicerad: F1000Research 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500957/
https://ncbi.nlm.nih.gov/pubmed/28713543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9259.2
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