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GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes

Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, ther...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: van den Broek, Evert, van Lieshout, Stef, Rausch, Christian, Ylstra, Bauke, van de Wiel, Mark A., Meijer, Gerrit A., Fijneman, Remond J.A., Abeln, Sanne
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500957/
https://ncbi.nlm.nih.gov/pubmed/28713543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9259.2
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