GeneBreak: detection of recurrent DNA copy number aberration-associated chromosomal breakpoints within genes

Development of cancer is driven by somatic alterations, including numerical and structural chromosomal aberrations. Currently, several computational methods are available and are widely applied to detect numerical copy number aberrations (CNAs) of chromosomal segments in tumor genomes. However, ther...

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Bibliografiske detaljer
Udgivet i:F1000Res
Main Authors: van den Broek, Evert, van Lieshout, Stef, Rausch, Christian, Ylstra, Bauke, van de Wiel, Mark A., Meijer, Gerrit A., Fijneman, Remond J.A., Abeln, Sanne
Format: Artigo
Sprog:Inglês
Udgivet: F1000Research 2017
Fag:
Software Tool Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500957/
https://ncbi.nlm.nih.gov/pubmed/28713543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.9259.2
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