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Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis
Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scal...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500891/ https://ncbi.nlm.nih.gov/pubmed/28675157 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15857 |
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