Megakaryocytes in Myeloproliferative Neoplasms Have Unique Somatic Mutations

Myeloproliferative neoplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with hyperproliferation of myeloid cells. They are driven by mutations in the hemopoietic stem cell, most notably JAK2(V617F), CALR, and MPL. Clinically, they have the propensity to progress...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Guo, Belinda B., Allcock, Richard J., Mirzai, Bob, Malherbe, Jacques A., Choudry, Fizzah A., Frontini, Mattia, Chuah, Hun, Liang, James, Kavanagh, Simon E., Howman, Rebecca, Ouwehand, Willem H., Fuller, Kathryn A., Erber, Wendy N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500825/
https://ncbi.nlm.nih.gov/pubmed/28502479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.03.009
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