Megakaryocytes in Myeloproliferative Neoplasms Have Unique Somatic Mutations

Myeloproliferative neoplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with hyperproliferation of myeloid cells. They are driven by mutations in the hemopoietic stem cell, most notably JAK2(V617F), CALR, and MPL. Clinically, they have the propensity to progress...

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Bibliografiska uppgifter
I publikationen:Am J Pathol
Huvudupphovsmän: Guo, Belinda B., Allcock, Richard J., Mirzai, Bob, Malherbe, Jacques A., Choudry, Fizzah A., Frontini, Mattia, Chuah, Hun, Liang, James, Kavanagh, Simon E., Howman, Rebecca, Ouwehand, Willem H., Fuller, Kathryn A., Erber, Wendy N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2017
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500825/
https://ncbi.nlm.nih.gov/pubmed/28502479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.03.009
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