Megakaryocytes in Myeloproliferative Neoplasms Have Unique Somatic Mutations

Myeloproliferative neoplasms (MPNs) are a group of related clonal hemopoietic stem cell disorders associated with hyperproliferation of myeloid cells. They are driven by mutations in the hemopoietic stem cell, most notably JAK2(V617F), CALR, and MPL. Clinically, they have the propensity to progress...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Guo, Belinda B., Allcock, Richard J., Mirzai, Bob, Malherbe, Jacques A., Choudry, Fizzah A., Frontini, Mattia, Chuah, Hun, Liang, James, Kavanagh, Simon E., Howman, Rebecca, Ouwehand, Willem H., Fuller, Kathryn A., Erber, Wendy N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2017
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500825/
https://ncbi.nlm.nih.gov/pubmed/28502479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.03.009
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