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The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats

On the basis of tissue-specific enzyme activity and inhibition by catalytic products, Hans Krebs first demonstrated the existence of multiple glutaminases in mammals. Currently, two human genes are known to encode at least four glutaminase isoforms. However, the phylogeny of these medically relevant...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Pasquali, Camila Cristina, Islam, Zeyaul, Adamoski, Douglas, Ferreira, Igor Monteze, Righeto, Ricardo Diogo, Bettini, Jefferson, Portugal, Rodrigo Villares, Yue, Wyatt Wai-yin, Gonzalez, Ana, Dias, Sandra Martha Gomes, Ambrosio, Andre Luis Berteli
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500818/
https://ncbi.nlm.nih.gov/pubmed/28526749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787291
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