The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats

On the basis of tissue-specific enzyme activity and inhibition by catalytic products, Hans Krebs first demonstrated the existence of multiple glutaminases in mammals. Currently, two human genes are known to encode at least four glutaminase isoforms. However, the phylogeny of these medically relevant...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Pasquali, Camila Cristina, Islam, Zeyaul, Adamoski, Douglas, Ferreira, Igor Monteze, Righeto, Ricardo Diogo, Bettini, Jefferson, Portugal, Rodrigo Villares, Yue, Wyatt Wai-yin, Gonzalez, Ana, Dias, Sandra Martha Gomes, Ambrosio, Andre Luis Berteli
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500818/
https://ncbi.nlm.nih.gov/pubmed/28526749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787291
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