The origin and evolution of human glutaminases and their atypical C-terminal ankyrin repeats

On the basis of tissue-specific enzyme activity and inhibition by catalytic products, Hans Krebs first demonstrated the existence of multiple glutaminases in mammals. Currently, two human genes are known to encode at least four glutaminase isoforms. However, the phylogeny of these medically relevant...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Pasquali, Camila Cristina, Islam, Zeyaul, Adamoski, Douglas, Ferreira, Igor Monteze, Righeto, Ricardo Diogo, Bettini, Jefferson, Portugal, Rodrigo Villares, Yue, Wyatt Wai-yin, Gonzalez, Ana, Dias, Sandra Martha Gomes, Ambrosio, Andre Luis Berteli
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500818/
https://ncbi.nlm.nih.gov/pubmed/28526749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.787291
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