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Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domains
Wnt signaling pathways are of significant interest in development and oncogenesis. The first step in these pathways typically involves the binding of a Wnt protein to the cysteine-rich domain (CRD) of a Frizzled receptor. Wnt-Frizzled interactions can be antagonized by secreted Frizzled-related prot...
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| Published in: | J Biol Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500790/ https://ncbi.nlm.nih.gov/pubmed/28533339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786269 |
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