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HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis

Aldosterone and the Mineralocorticoid Receptor (MR) control hydroelectrolytic homeostasis and alterations of mineralocorticoid signaling pathway are involved in the pathogenesis of numerous human diseases, justifying the need to decipher molecular events controlling MR expression level. Here, we sho...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lema, Ingrid, Amazit, Larbi, Lamribet, Khadija, Fagart, Jérôme, Blanchard, Anne, Lombès, Marc, Cherradi, Nadia, Viengchareun, Say
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500589/
https://ncbi.nlm.nih.gov/pubmed/28684740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04838-8
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