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Sharing of Genes and Pathways Across Complex Phenotypes: A Multilevel Genome-Wide Analysis

Evidence from genome-wide association studies (GWAS) suggest that pleiotropic effects on human complex phenotypes are very common. Recently, an atlas of genetic correlations among complex phenotypes has broadened our understanding of human diseases and traits. Here, we examine genetic overlap, from...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Gui, Hongsheng, Kwan, Johnny S., Sham, Pak C., Cherny, Stacey S., Li, Miaoxin
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500153/
https://ncbi.nlm.nih.gov/pubmed/28495956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.198150
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