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A Knowledge-Based Weighting Framework to Boost the Power of Genome-Wide Association Studies
BACKGROUND: We are moving to second-wave analysis of genome-wide association studies (GWAS), characterized by comprehensive bioinformatical and statistical evaluation of genetic associations. Existing biological knowledge is very valuable for GWAS, which may help improve their detection power partic...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3013112/ https://ncbi.nlm.nih.gov/pubmed/21217833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014480 |
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