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Risk Prediction of Complex Diseases from Family History and Known Susceptibility Loci, with Applications for Cancer Screening
Risk prediction based on genomic profiles has raised a lot of attention recently. However, family history is usually ignored in genetic risk prediction. In this study we proposed a statistical framework for risk prediction given an individual's genotype profile and family history. Genotype info...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3146722/ https://ncbi.nlm.nih.gov/pubmed/21529750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.04.001 |
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