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Risk Prediction of Complex Diseases from Family History and Known Susceptibility Loci, with Applications for Cancer Screening

Risk prediction based on genomic profiles has raised a lot of attention recently. However, family history is usually ignored in genetic risk prediction. In this study we proposed a statistical framework for risk prediction given an individual's genotype profile and family history. Genotype info...

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Detalhes bibliográficos
Main Authors: So, Hon-Cheong, Kwan, Johnny S.H., Cherny, Stacey S., Sham, Pak C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146722/
https://ncbi.nlm.nih.gov/pubmed/21529750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.04.001
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