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Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies
Recently genome-wide association studies (GWAS) have identified numerous susceptibility variants for complex diseases. In this study we proposed several approaches to estimate the total number of variants underlying these diseases. We assume that the variance explained by genetic markers (Vg) follow...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2984437/ https://ncbi.nlm.nih.gov/pubmed/21103334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013898 |
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