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Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies

Recently genome-wide association studies (GWAS) have identified numerous susceptibility variants for complex diseases. In this study we proposed several approaches to estimate the total number of variants underlying these diseases. We assume that the variance explained by genetic markers (Vg) follow...

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Bibliografische gegevens
Hoofdauteurs: So, Hon-Cheong, Yip, Benjamin H. K., Sham, Pak Chung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984437/
https://ncbi.nlm.nih.gov/pubmed/21103334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013898
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