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Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination

Radioiodinated pharmaceuticals are convenient tracers for clinical and research investigations because of the relatively long half‐lives of radioactive iodine isotopes (i.e., (123)I, (124)I, and (131)I) and the ease of their chemical insertion. Their application in radionuclide imaging and therapy m...

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書誌詳細
出版年:European J Org Chem
主要な著者: Cavina, Lorenzo, van der Born, Dion, Klaren, Peter H. M., Feiters, Martin C., Boerman, Otto C., Rutjes, Floris P. J. T.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499721/
https://ncbi.nlm.nih.gov/pubmed/28736501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201601638
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