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Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination

Radioiodinated pharmaceuticals are convenient tracers for clinical and research investigations because of the relatively long half‐lives of radioactive iodine isotopes (i.e., (123)I, (124)I, and (131)I) and the ease of their chemical insertion. Their application in radionuclide imaging and therapy m...

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Detalhes bibliográficos
Publicado no:European J Org Chem
Main Authors: Cavina, Lorenzo, van der Born, Dion, Klaren, Peter H. M., Feiters, Martin C., Boerman, Otto C., Rutjes, Floris P. J. T.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499721/
https://ncbi.nlm.nih.gov/pubmed/28736501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201601638
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