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Design of Radioiodinated Pharmaceuticals: Structural Features Affecting Metabolic Stability towards in Vivo Deiodination

Radioiodinated pharmaceuticals are convenient tracers for clinical and research investigations because of the relatively long half‐lives of radioactive iodine isotopes (i.e., (123)I, (124)I, and (131)I) and the ease of their chemical insertion. Their application in radionuclide imaging and therapy m...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:European J Org Chem
Päätekijät: Cavina, Lorenzo, van der Born, Dion, Klaren, Peter H. M., Feiters, Martin C., Boerman, Otto C., Rutjes, Floris P. J. T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499721/
https://ncbi.nlm.nih.gov/pubmed/28736501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201601638
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