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G-quadruplex structure of an anti-proliferative DNA sequence

AGRO100 (also known as AS1411) is a G-rich oligonucleotide that has long been established as a potent anti-cancer aptamer. However, the structure of AGRO100 remained unresolved, due to the co-existence of multiple different G-quadruplex conformations. We identified a DNA sequence named AT11, derived...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Do, Ngoc Quang, Chung, Wan Jun, Truong, Thi Hong Anh, Heddi, Brahim, Phan, Anh Tuân
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499593/
https://ncbi.nlm.nih.gov/pubmed/28549181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx274
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