Identifying transposon insertions and their effects from RNA-sequencing data

Insertional mutagenesis using engineered transposons is a potent forward genetic screening technique used to identify cancer genes in mouse model systems. In the analysis of these screens, transposon insertion sites are typically identified by targeted DNA-sequencing and subsequently assigned to pre...

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Bibliografiska uppgifter
I publikationen:Nucleic Acids Res
Huvudupphovsmän: de Ruiter, Julian R., Kas, Sjors M., Schut, Eva, Adams, David J., Koudijs, Marco J., Wessels, Lodewyk F. A., Jonkers, Jos
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2017
Ämnen:
Computational Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499543/
https://ncbi.nlm.nih.gov/pubmed/28575524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx461
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