Enhanced Sensitivity of Neil1(−/−) Mice to Chronic UVB Exposure

Oxidative stress and reactive oxygen species (ROS)-induced DNA base damage are thought to be central mediators of UV-induced carcinogenesis and skin aging. However, increased steady-state levels of ROS-induced DNA base damage have not been reported after chronic UV exposure. Accumulation of ROS-indu...

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Bibliographic Details
Published in:DNA Repair (Amst)
Main Authors: Calkins, Marcus J, Vartanian, Vladimir, Owen, Nichole, Kirkali, Guldal, Jaruga, Pawel, Dizdaroglu, Miral, McCullough, Amanda K., Lloyd, Stephen R.
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499380/
https://ncbi.nlm.nih.gov/pubmed/27818081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.10.010
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