Adoptively transferred Vγ9Vδ2 T cells show potent antitumor effects in a preclinical B cell lymphomagenesis model

A central issue for adoptive cellular immunotherapy is overcoming immunosuppressive signals to achieve tumor clearance. While γδ T cells are known to be potent cytolytic effectors that can kill a variety of cancers, it is not clear whether they are inhibited by suppressive ligands expressed in tumor...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Zumwalde, Nicholas A., Sharma, Akshat, Xu, Xuequn, Ma, Shidong, Schneider, Christine L., Romero-Masters, James C., Hudson, Amy W., Gendron-Fitzpatrick, Annette, Kenney, Shannon C., Gumperz, Jenny E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499361/
https://ncbi.nlm.nih.gov/pubmed/28679955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93179
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