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Roles of diacylglycerols and ceramides in hepatic insulin resistance

Although ample evidence links hepatic lipid accumulation with hepatic insulin resistance, the mechanistic basis of this association is incompletely understood and controversial. Diacylglycerols and ceramides have emerged as the two best-studied putative mediators of lipid-induced hepatic insulin res...

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Bibliographic Details
Published in:Trends Pharmacol Sci
Main Authors: Petersen, Max C., Shulman, Gerald I.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499157/
https://ncbi.nlm.nih.gov/pubmed/28551355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.04.004
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