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Roles of diacylglycerols and ceramides in hepatic insulin resistance

Although ample evidence links hepatic lipid accumulation with hepatic insulin resistance, the mechanistic basis of this association is incompletely understood and controversial. Diacylglycerols and ceramides have emerged as the two best-studied putative mediators of lipid-induced hepatic insulin res...

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Detalhes bibliográficos
Publicado no:Trends Pharmacol Sci
Main Authors: Petersen, Max C., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499157/
https://ncbi.nlm.nih.gov/pubmed/28551355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2017.04.004
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