Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery

PURPOSE: To develop a new intradermal antigen delivery system by coating microneedle arrays with lipid bilayer-coated, antigen-loaded mesoporous silica nanoparticles (LB-MSN-OVA). METHODS: Synthesis of MSNs with 10-nm pores was performed and the nanoparticles were loaded with the model antigen ovalb...

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Dettagli Bibliografici
Pubblicato in:Pharm Res
Autori principali: Tu, Jing, Du, Guangsheng, Reza Nejadnik, M., Mönkäre, Juha, van der Maaden, Koen, Bomans, Paul H. H., Sommerdijk, Nico A. J. M., Slütter, Bram, Jiskoot, Wim, Bouwstra, Joke A., Kros, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498618/
https://ncbi.nlm.nih.gov/pubmed/28536970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2177-4
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