Mesoporous Silica Nanoparticle-Coated Microneedle Arrays for Intradermal Antigen Delivery

PURPOSE: To develop a new intradermal antigen delivery system by coating microneedle arrays with lipid bilayer-coated, antigen-loaded mesoporous silica nanoparticles (LB-MSN-OVA). METHODS: Synthesis of MSNs with 10-nm pores was performed and the nanoparticles were loaded with the model antigen ovalb...

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Publicat a:Pharm Res
Autors principals: Tu, Jing, Du, Guangsheng, Reza Nejadnik, M., Mönkäre, Juha, van der Maaden, Koen, Bomans, Paul H. H., Sommerdijk, Nico A. J. M., Slütter, Bram, Jiskoot, Wim, Bouwstra, Joke A., Kros, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498618/
https://ncbi.nlm.nih.gov/pubmed/28536970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2177-4
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