Cationic Liposomes Loaded with a Synthetic Long Peptide and Poly(I:C): a Defined Adjuvanted Vaccine for Induction of Antigen-Specific T Cell Cytotoxicity

For effective cancer immunotherapy by vaccination, co-delivery of tumour antigens and adjuvants to dendritic cells and subsequent activation of antigen-specific cytotoxic T cells (CTLs) is crucial. In this study, a synthetic long peptide (SLP) harbouring the model CTL epitope SIINFEKL was encapsulat...

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Bibliografiska uppgifter
I publikationen:AAPS J
Huvudupphovsmän: Varypataki, Eleni Maria, van der Maaden, Koen, Bouwstra, Joke, Ossendorp, Ferry, Jiskoot, Wim
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287297/
https://ncbi.nlm.nih.gov/pubmed/25387996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-014-9686-4
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