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BRD4 inhibition for the treatment of pathological organ fibrosis

Fibrosis is defined as excess deposition of extracellular matrix, resulting in tissue scarring and organ dysfunction. It is estimated that 45% of deaths in the developed world are due to fibrosis-induced organ failure. Despite the well-accepted role of fibrosis in the pathogenesis of numerous diseas...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Stratton, Matthew S., Haldar, Saptarsi M., McKinsey, Timothy A.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497817/
https://ncbi.nlm.nih.gov/pubmed/28721198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.11339.1
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