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Increased PD-1(+) and TIM-3(+) TILs during cetuximab therapy inversely correlates with response in head and neck cancer patients

Despite emerging appreciation for the important role of immune checkpoint receptors in regulating the effector functions of T cells, it is unknown whether their expression is involved in determining the clinical outcome in response to cetuximab therapy. We examined the expression patterns of immune...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Jie, Hyun-Bae, Srivastava, Raghvendra M., Argiris, Athanassios, Bauman, Julie E., Kane, Lawrence P., Ferris, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497750/
https://ncbi.nlm.nih.gov/pubmed/28408386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-16-0333
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