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PRL-3 Engages the Focal Adhesion Pathway in Triple-Negative Breast Cancer Cells to Alter Actin Structure and Substrate Adhesion Properties Critical for Cell Migration and Invasion

Triple-negative breast cancers (TNBCs) are among the most aggressive cancers characterized by a high propensity to invade, metastasize and relapse. We previously reported that the TNBC-specific inhibitor, AMPI-109, significantly impairs the ability of TNBC cells to migrate and invade by reducing lev...

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Podrobná bibliografie
Vydáno v:Cancer Lett
Hlavní autoři: Gari, Hamid H., DeGala, Gregory D., Ray, Rahul, Lucia, M. Scott, Lambert, James R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497588/
https://ncbi.nlm.nih.gov/pubmed/27452906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.07.017
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