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PRL-3 Engages the Focal Adhesion Pathway in Triple-Negative Breast Cancer Cells to Alter Actin Structure and Substrate Adhesion Properties Critical for Cell Migration and Invasion
Triple-negative breast cancers (TNBCs) are among the most aggressive cancers characterized by a high propensity to invade, metastasize and relapse. We previously reported that the TNBC-specific inhibitor, AMPI-109, significantly impairs the ability of TNBC cells to migrate and invade by reducing lev...
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| Publicado no: | Cancer Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5497588/ https://ncbi.nlm.nih.gov/pubmed/27452906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.07.017 |
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